The Essentials to Micromanipulation

What it takes to perform micromanipulation (and microinjection) is as follows.

Microscope
Mounting Adaptor(s) to mount micromanipulators onto a microscope
Coarse manipulator(s) to quickly place a micropipette in the field of view and move it close to the specimen.
Fine micromanipulator(s) to perform the final approach to the cell and insert the micropipette into the cell.
Microinjector(s) to hold the egg or inject solution into it.
Anti-vibration base to absorb the external vibration and prevent its transmission to the microscope.

The following instruments are required to produce and fabricate micropipettes/microelectrodes.

Micropipette/Microelectrode Puller

It is used to pull a glass capillary into a micropipette/microelectrode.

Microforge

It is used to break, fire-polish, put a spike on or bend a micropipette/microelectrode.

Micropipette/Microelectrode Grinder

It is used to bevel the tip of a micropipette/microelectrode.

It is important that micromanipulators used in electrophysiology, particularly for slice patch clamping, be free from vibration and drift. Anything that causes a micropipette to move can ruin an experiment. Therefore, micromanipulators used for this type of work need to be securely mounted and allow only minimal drift.